Nội dung text Mini Katzung ( Al HaYaT ).pdf
iii Contents Preface v par t I BASIC PRINCIPLES 1 1. Introduction 1 2. Pharmacodynamics 16 3. Pharmacokinetics 26 4. Drug Metabolism 35 5. Pharmacogenomics 41 par t II AUTONOMIC DRUGS 47 6. Introduction to Autonomic Pharmacology 47 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 60 8. Cholinoceptor Blockers & Cholinesterase Regenerators 69 9. Sympathomimetics 76 10. Adrenoceptor Blockers 85 par t III CARDIOVASCULAR DRUGS 93 11. Drugs Used in Hypertension 93 12. Drugs Used in the Treatment of Angina Pectoris 103 13. Drugs Used in Heart Failure 112 14. Antiarrhythmic Drugs 121 15. Diuretics & Other Drugs That Act on the Kidney 132 par t IV DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE 143 16. Histamine, Serotonin, & the Ergot Alkaloids 143 17. Vasoactive Peptides 152 18. Prostaglandins & Other Eicosanoids 158 19. Nitric Oxide, Donors, & Inhibitors 165 20. Drugs Used in Asthma & Chronic Obstructive Pulmonary Disease 169 par t V DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM 179 21. Introduction to CNS Pharmacology 179 22. Sedative-Hypnotic Drugs 186 23. Alcohols 194 24. Antiseizure Drugs 201 25. General Anesthetics 208 26. Local Anesthetics 216 27. Skeletal Muscle Relaxants 221 28. Drugs Used in Parkinsonism & Other Movement Disorders 229 29. Antipsychotic Agents & Lithium 236 30. Antidepressants 244 31. Opioid Analgesics & Antagonists 252 32. Drugs of Abuse 260