Tiêu đề Biohacking Bible - A Neuropharmacology Encyclopedia ✅

by ryderlefeg on Discord and editors Revised by Meso aka Deya Rabbie Neuropharmacology, B.Sc. † RIP Last updated on 12-07-2025 Check out the GPT bot Biohacker (beta version). And don’t forget to check out r/prefrontal as well. ---------------------------------------
If you want to download or print this book, it can be purchased on Gumroad. If you want to donate and support me, my PayPal (paste your email in the message) and crypto addresses (most preferred) are: SOL: 516mqdwzZkerw1PT64X7PaKWT13hSrT6W2fGWjBpe4gh ERC-20: 0xDaa1cad37f4da58B841365d96d140eD949f56E49 BTC: bc1qjwsr82d8slz06hexzus2kw47r94xe3y38hh7wf LTC: ltc1qz6hkcwdh4us0nu6hzclkcgtvrsgjgpxmsc5j3j XMR: 48qYHKaDDGFExz4hSAiZTi8Z623y5ehiC8kDxLNWRWCGZRQc5Nuby1G5edDz9BskD7L9CYhZXytkY5ip8XZ6qy1w2LL6k3r --------------------------------------- This is an overview of various drugs ranging from antidepressants to psychedelics in light of pharmacological and neuroscientific research. I focus on the substances I think would be of most help to the hypodopaminergic phenotype of neuropsychiatric disorders (ie. anhedonia, depression/anxiety, PSSD, DPDR and ADHD). Depression, poor motivation and focus are often attributed to low dopamine and norepinephrine but low acetylcholine activity is also a factor. Acetylcholine is needed to sustain attention, and a lack of acetylcholine due to low dietary choline can contribute to ADHD symptoms; make sure you eat enough choline-rich food like eggs, or supplement with CDP-choline/alpha-GPC. MAOIs increase both dopamine and norepinephrine concentrations which is why they are highly regarded. One of the main reasons behind hypodopaminergic symptoms such as anhedonia, social withdrawal, short attention span and sexual dysfunction is supersensitivity to serotonin or excessive serotonergic signaling. Serotonin acts as a counterbalance to dopamine in the brain for the most part (it is brain region specific; cortical 5-HT2A increases dopamine release to the NAc, while hypothalamic 5-HT1A increases dopamine , β-endorphin, oxytocin there), so one of the best ways to resolve this is to block specific serotonin receptors. --------------------------------------- NOTE: none of this is medical advice. These are mainly notes I’ve written after years of research. Some of the material mentioned in this ebook is experimental and is marked as such. Be sure to consult a licensed physician before attempting to self-medicate. It is NOT advisable to dabble with nootropics until you first adopt a healthy lifestyle by getting your gut, immune system, blood levels, hormones in the best shape possible, and adopting a healthy diet (including drinking filtered water). Remember to also get thyroid and blood panels done. Ideally test for all vitamins, minerals and hormones but if you can’t get your doctor to refer you for those tests, then get lab tests done yourself at a Spectracell lab or order an Idealabs kit (easiest and cheapest method).