Tiêu đề Biomolecules - 01.pdf ✅

1 JEE Advanced 2024 Biomolecules 1. Find iso-electric point of given amino acid CH3 – CH – CO2H NH3  pka = 2.2, pkb = 4.4 (A) 3.3 (B) 5.9 (C) 9.6 (D) 11.8 2. Find iso-electric point of the given amino acid H – O – C – CH2 – CH2 – CH – CO2H O NH3  (pk = 4) a (pk = 9) b (A) 5.5 (B) 6.5 (C) 4.5 (D) 5 3. Which of the molecules below will react with Ag+ ? (i) HO OCH3 CH2OH O HO HO HO (ii) HN2 NHCH2CH2 OH HO O HO (iii) O OH OH OH OH OH O O HO HO HO (iv) O OH OH OH OH OH HO O O HO HO (v) HO OH CH2OH O HO HO HO OCH2CH3 (vi) HO OH OCH3 CH2 OH OH OH O O HO O HO HO HO (A) (i), (iii) and (v) (B) (ii) and (iv) (C) (iv) and (vi) (D) (i), (ii), (iii) and (vi) 4. Which of the compounds(A-D) depicted above is NOT a hemiacetal linkage? (a) HO HO HO OH O O HO OH HO O OH (b) HO HO HO OH O HO O HO (c) HO HO O HO O OH (d) HO OH O O OH O O OH OH OH OH HO OH O OH OH (A) Compound a (B) Compound b (C) Compound c (D) Compound d (E) None of the above (they are all hemiacetals) DPP-01
2 5. At iso-electric point: (A) Concentration of cation is equal to concentration of anion (B) Net charge is zero (C) Maximum conc. of di-pole ion (Zwitter ion) will be present (D) All of the above 6. Which of the following amino acid has lowest iso- electric point ? (A) Glycine (B) Alanine (C) Aspartic acid (D) Lysine 7. Which amino acid does not contain chiral centre? (A) Valine (B) Leucine (C) Glycine (D) Iso-leucine 8. Which of the following is Sanger reagent? (A) 2,4-Di-nitro fluorobenzene (B) Phenyl isocyanane (C) 2,4-Di-nitro chlorobenzene (D) 2,4-Di-nitro-iodobenzene 9. HC = N – NH – Ph HC = N – NH – Ph HO H H OH OH H CH2OH The given osazone can be obtained by: (A) D-glucose (B) D-mannose (C) D-Idose (D) Both (A) & (B) 10. Which of the following represents the anomer of the compound shown? H H OH O OHCH2 H H OH OH (A) H H OH O OHCH2 H H OH HO (B) H H OH O OHCH2 H OH H HO (C) OH HO O HOH2C H OH H H H (D) None of these 11. The N-base which differentiate DNA with RNA is (A) Cytosine (B) Uracil (C) Ademine (D) Guanine 12. Which one of the following bases is not present in DNA? (A) Cytosine (B) Thymine (C) Quinoline (D) Adenine 13. The configuration of the C-2 epimer of D-glucose is - (A) 2R, 3S, 4R, 5S (B) 2S, 3S, 4R, 5R (C) 2S, 3R, 4S, 5R (D) 2R, 3S, 4R, 5R
3 14. Peptide linkage is – (A) – C – O O (B) – C – NH2 O (C) – C – NH – O (D) – C – NH – NH2 O 15. D( ) − – Erythrose NaBH4 ⎯⎯⎯→(P) D( ) – Threose (R) NaBH4 − ⎯⎯⎯→ Which of the following statement is correct about P and R ? (A) Both are optically active (B) Both are optically inactive (C) P is optically inactive and R is optically active (D) Neither P nor R has asymmetric carbon 16. The monomer of nucleic are heldc together by (A) Phosphoester linkage (B) Amide linkage (C) Glycosidic linkage (D) Ester linkage 17. Select the incorrect statement about Nylon 2-nylon-6. (A) It is a copolymer (B) It is biodegradable (C) It is an alternating polymaide (D) It is made up of CH3 – CH – COOH NH2 and H2N(CH2)5COOH. 18. Which of the vitamins given below is water soluble? (A) Vitamin E (B) Vitamin K (C) Vitamin C (D) Vitamin D 19. Select the correct statement: (A) Glycosides do not undergo mutarotation (B) All OH groups of a cyclic monosaccharides are converted to ethers by treatment with base and an alkyl halide (C) -D glucose reacts with Ag O2 and excess CH I3 to form tetramethyl ether (D) D-glucose upon treatment with warm HNO3 from D-gluconic acid 20. Amino acids are synthesised from (A) -halo acids by reaction with NH3 (B) Aldehydes by reaction with NH3 and cyanide ion followed by hydrolysis (C) Alkyl halides by reaction with the enolate anion derived from diethyl acetamidomalonate\& hydrolysis (D) Alcohols by reaction with NH3 and CN− ion followed by hydrolysis
4 Answer Key 1. (B) 2. (C) 3. (C) 4. (C) 5. (D) 6. (C) 7. (C) 8. (A) 9. (D) 10. (B) 11. (B) 12. (C) 13. (B) 14. (C) 15. (C) 16. (A) 17. (D) 18. (C) 19. (A, B ) 20. (A, B, C)