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RADIO PHARMACEUTICALS Radiopharmaceuticals are the radioactive substances or radioactive drugs for substances or radioactive drugs for diagnostic or therapeutic interventions diagnostic or therapeutic interventions COMPOSITION a radioactive isotope that can be injected safely into the body, and a carrier molecule which delivers the isotope to the area to be treated or examined. RADIOISOTOPE *A version of a chemical element that has a version of a chemical element that has an unstable nucleus and emits radiation during its decay to a stable form. *All isotopes are not radioisotopes WORKING :- The radiotracer is injected into vein,emits gamma radiation as it decays.A gamma camera scans the radiation area and creates a image HAlF LIFE of Radiopharmaceuticals *Physical half ife refers to the time needed for a radio active substance to lose 50% of its activity through decay *Biological Half life refers to the time needed for the body to eliminate 50% of the radioactive substance *The combined effect of physical and biological half life required for the radioactivity of an administered radioisotopic to decrease 50% Uses *Therapeutic *Diagnosing Therapeutic *Designed to deliver therapeutic dose of ionizing radiation to specific disease site, such as cancerous tumors with high specificity in the body. *Historically, used to treat Thyroid cancer, Graves’ disease, hyperthyroidism, and bone pain Diagnosing *used to derive detailed description of the morphology and dynamic functioning of the various internal organs of the body. ADVANTAGES *It can be used as diagnosis and treatment of patients *It is common cure to cancers *Can treat multiple disease sites *Widely available mode of treatment *Can provide fast onset of pain relief *Directly treats tumor, especially useful for bone metastasis *Single dose is effective for some patients *Nuclear medicine tests can be performed on children *Nuclear medicine procedures are cost effective and painless DISADVANTAGES *Nuclear medicine tests are not recommended for pregnant women because unborn babies have a greater sensitivity to radiation than children or adults
4)Route of administration 5)Total radioactive present 6)Expiry date 7)Batch number 8)For solution , total volume 9)Any special storage requirements with respective to temperature , light , name and any cloudy substance added and microbial preservatives PLACK CARDS LABELLS: 1) Type 1 radioactive white 1 2) Type 2 radioactive yellow 2 3) Type 3 radioactivity yellow 3 *Type 1 radioactive white 1 Almost no radiation , the maximum allowable radioactivity is 0.5 mrem/hr on the package surface *Type 2 radioactive yellow 2 Low radiation level , the maximum allowable radioactivity is 50mrem /hr on the package surface and 1 mrem /hr at 3 feet from the package *Type 3 radioactivity yellow 3 High levels of radiation , maximum allowable radio activity is 200 mrem/hr on the package surface and 10mrem/hr at 3 feet from the package