Title 8. DRUG UTILISATION EVALUATION (DUE) AND REVIEW (DUR).pdf ✅

PHARMD GURU Page 1 DRUG UTILISATION EVALUATION (DUE) According to WHO, Drug Utilization evaluation is defined as the marketing, distribution, prescription and use of drugs in society, with special emphasis on the resulting medical, social and economic consequences. Drug Utilization Evaluation (DUE) is an ongoing authorized and systematic quality improvement process, designed to:  To optimize drug use by developing criteria and standards.  To educate clinicians and other Health Care Professionals (HCP), to increase appropriate drug use.  To provide feedback of results obtained during study to clinicians and other HCP.  To review drug use.  To analyze prescription pattern. TYPES OF DUE: 1) Quantitative DUE studies. 2) Qualitative DUE studies. DUE COMMITTEE:  DUE Committee should be composed of physicians, pharmacists and other relevant health-care professionals.  The committee must include professionals with on interest in improving drug therapy in the hospital and have ready access to experts in the medicine, surgery and major hospital specialists.  Pharmacists generally play a major role in the delivery of DUE and it is usual for the committee to include pharmacy department representation. ROLE OF PHARMACIST IN DUE:  Planning, organizing and implementing a DUE program.  Program, development, supervision and coordination.  Education of hospital staff about DUE in conceptual an practical terms. DRUG UTILISATION EVALUATION (DUE) AND REVIEW (DUR)
PHARMD GURU Page 2  Promotion of the goals and objectives of DUE.  Development or review of audit criteria, guidelines, study protocols and educational materials.  Development of data collection, analysis and report writing.  Documentation of program outcome, effectiveness and cost benefits.  Participation in hospital committees concerned with quality assurance in general and drug usage.  Presentation of DUE results at meeting and conferences.  Publication of results in peer-viewed journals. STEPS IN DRUG UTILIZATION EVALUATION: The steps of a DUE are as follows: STEP 1: ESTABLISH RESPONSIBILITY:  It is the responsibility of the DTC to establish procedures for the implementation of a DUE program.  This includes appointing a responsible member of the DTC or a subcommittee to monitor and supervise the DUE process in the hospital or clinics. PLANNING DATA COLLECTION EVALUATION FEED BACK OF RESULTS INTERVENTION RE- EVALUATION FEED BACK OF RESULTS
PHARMD GURU Page 3  Ideally the DTC should establish annual plans, outlining which medicines or clinical conditions will be a part of the DUE process. STEP 2: DEVELOP THE SCOPE OF ACTIVITIES AND DEFINE THE OBJECTIVES: The DTC should decide upon the objectives of the DUE and the scope of the activities necessary. The scope can be very extensive or it can focus on a single aspect of drug therapy and will depend upon the type of problem identified, for example:  Overuse of a more expensive medicine when a cheaper equivalent is available, as revealed in aggregate data.  Incorrect use (indication, dosage, administration) of a particular drug, as revealed in patient charts, medication error reports, ADR reports.  Inappropriate choices of antibiotic, as revealed in antibiotic sensitivity reports.  Poor dispensing process, as revealed by patient complaints or feedback. Due to the large number of medicines available at a hospital or clinic, the DTC must concentrate on those medicines with the highest potential for problems in order to get the most return on the work involved. These high-priority areas include:  High-volume drugs.  Expensive drugs.  Drugs with a narrow therapeutic index.  Drugs with a high incidence of ADRs.  Critically important therapeutic categories, for example cardiovascular, emergency, toxicology, intravenous drugs, chemotherapy and narcotic analgesics.  Antimicrobial drugs, prophylactic and therapeutic.  Drugs undergoing evaluation for addition to the formulary.  Drugs used for non-labelled indications.  Drugs used in high-risk patients.  Common clinical conditions often poorly treated. STEP 3: ESTABLISH CRITERIA FOR REVIEW OF THE MEDICINE: DUE criteria are statements that define correct drug usage with regard to various components. Criteria for the use of any medicine should be established using the hospital’s STGs (assuming that they have been correctly developed). In the absence of hospital STGs, criteria may be based on recommendations from national or other