Title 6. REPAIRS OF WOUNDS IN THE SKIN.pdf ✅

PHARMD GURU Page 1 Healing of skin wounds provides a classical example of combination of regeneration and repair described above. Wound healing can be accomplished in one of the following two ways: 1) Healing by first intention (primary union) 2) Healing by second intention (secondary union). 1)HEALING BY FIRST INTENTION (PRIMARY UNION): This is defined as healing of a wound which has the following characteristics: i) Clean and uninfected; ii) Surgically incised; iii) Without much loss of cells and tissue; and iv) Edges of wound are approximated by surgical sutures. The sequence of events in primary union is illustrated in Fig. 6.42 and described below: 1) INITIAL HAEMORRHAGE: Immediately after injury, the space between the approximated surfaces of incised wound is filled with blood which then clots and seals the wound against dehydration and infection. REPAIRS OF WOUNDS IN THE SKIN