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Content text 4. DRUG UTILIZATION REVIEW.pdf


PHARMD GURU Page 2  Participation in hospital committees concerned with quality assurance in general and drug usage.  Presentation of DUE results at meeting and conferences.  Publication of results in peer-viewed journals. FUNCTIONS OF DUE COMMITTEE:  The committee should draft and approve the policies and procedures.  Establish and maintain adequate means of communication with hospital administration and other relevant hospital committee.  Medical and other hospital staff should understand that the DUE program is a continuous quality improvement activity designed to ensure safe and effective drug use.  The committee should prepare a schedule including a yearly meeting and selecting and approving criteria, evaluating data, designing interventions and reviewing the program.  The committee should develop or review standards and criteria of DUE studies based on their knowledge, experience and literature findings.  Reviewing the data generated from study.  Initially, monthly meetings may be necessary to discuss start up problem and make corrections in the program.  Later quarterly meetings may be sufficient.  The committee should ensure compliance with good clinical research guidelines such as maintaining the confidentiality of all patients’ data.
PHARMD GURU Page 3 DUE CYCLE:  It is important to keep in mind that DUE operates in a repeating cycle.  The DUE cycle should include the following seven major activities or phases: 1) Planning (step 1-4) 2) Data collection (step 5) 3) Evaluation (step 6) 4) Feedback if results (step 7) 5) Interventions (step 8) 6) Re-evaluation (step 9-10) 7) Feedback of results (step 11) METRICS USED IN DRUG UTILIZATION EVALUATION: 1) Defined daily dose (DDD): The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. It can be done to only products which is approved and marketed at least in one country. PLANNING DATA COLLECTION EVALUATION FEEDBACK OF RESULTS INTERVENTION RE-EVALUATION FEED BACK OF RESULTS DUE CYCLE

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