Title 4. BSCKII. Ngo Thi Trang (UPD 0104).pdf ✅

Content 1. Anatomy and function of the subchondral bone 2. Subchondral bone remodeling in OA 3. Current and future therapies for OA subchondral bone remodeling

Anatomy of the Subchondral bone • Subchondral bone1 : underlying the calcified cartilage and tidemark, two anatomic entities: • Subchondral bone plate a thin cortical lamella, lying immediately beneath the calcified cartilage. • Subchondral trabecular bone: deeper bone structure. NCC, non-calcified cartilage; CC, calcified cartilage; SBP, subchondral bone plate; STB, subchondral trabecular bone. Arrows: the tidemark;