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Content text 3. TS.BS. Pham Chinh Nghia (UPD 2503).pdf

Intermittent fasting reduces crystal-induced inflammation PHAM Chinh Nghia, MD, PHD Department of internal medicine - Haiphong university of Medicine and Pharmacy BIOSCAR U1132 Research unit – Paris - France
INTRODUCTION ▪ Microcrystalline disease: Formation of MonoSodium Urate (MSU) and Calcium PyroPhosphate (CPP) crystals ▪ Crystals are responsible for acute inflammation MSU CPP Microcrystals
INTRODUCTION Crystal-induced inflammation depends on interleukin-1β Designed with biorender
INTRODUCTION What is the mechanism? Dessein et al., 2000 Caloric restriction reduces crystal-induced inflammation N=13

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