Title Updates on adjuvant treatment of uterine sarcoma - sara nassar.pdf ✅

UPDATES ON ADJUVANT THERAPIES FOR UTERINE SARCOMAS DR. SARA NASSER MRCOG DEPARTMENT OF GNYECOLOGY WITH CENTER OF ONCOLOGICAL SURGERY CHARITE COMPREHENSIVE CANCER CENTER CHARITE GLOBAL HEALTH CENTER VICE-PRESIDENT PAN-ARABIAN RESEARCH SOCIETY OF GYNECOLOGIC ONCOLOGY BERLIN, GERMANY
GYN Rare Tumors: Germcell Tumors Gyn-Sarcomas Genital NET Sex cord stromal tumors GTDs • Immature Teratoma • Yolk sac tumor • Dysgerminoma • Chorion Carcinomas • Invasive Moles • Neuroendocrine Carcinoma • Adulter/Juvenile Granulosacell tumors • Sertoli-Leydigcell-Tumors • Leiomyosarcoma • Endometrial Stromal sarcoma • Undifferentiated Stromal sarcoma
Histological Subtypes of GYN Sarcomas: • Uterine Leiomyosarcoma (uLMS): 63% High-grade tumor, associated with complex karyotype • Endometrial stromal sarcoma (ESS): 21% Low-grade tumor, expression of hormonal receptors • Adenosarcoma (AS): 6% Low-grade tumor, ± sarcomatous overgrowth • Undifferentiated endometrial Sarcoma (UES): 5% Low-grade tumor, no hormonal sensitivity
Risk Factors
ARE UTERINE SARCOMAS JUST ANOTHER TYPE OF SOFT TISSUE SARCOMA?