Title 1. Dr Luong Ngoc Trung.pdf ✅

NEW OPPORTUNITIES AND CHALLENGES FOR EARLY-STAGE OF NON-SMALL-CELL LUNG CANCER (NSCLC) • LUONG NGOC TRUNG, MD • Head Of Thoracic, Vascular and Endovascular Surgery Department • FV Hospital, Viet Nam

3 Survival of NSCLC at 5 years Adapted from Global Data. 2016. aDiagnosis statistics based on 7 major market countries (EU5, US, and Japan). EU-5 = European Union Five (France, Germany, Italy, Spain, and United Kingdom); NSCLC = non-small cell lung cancer; US = United States. 1. Deslypere G et al. Ther Adv Med Oncol. 2018;10:1-11. 2. GlobalData.EpiCast Report Non-Small Cell Lung Cancer (NSCLC) – Epidemiology Forecast to 2025. Accessed February 5, 2021. 3. World Health Organization. Cancer. 2018. Accessed February 21, 2021. 4. American Cancer Society. Key Statistics for Lung Cancer. Accessed February 5, 2021. 5. Datta D et al. Chest. 2003;123:2096-2103. 6. Le Chevalier et al. Ann Oncol. 2010;21:vii196-vii198. 7. Cagle PT et al. Arch Pathol Lab Med. 2013;137:1191-1198. stage I stage II stage III stage IV ( survival at 5 yrs1 68–92% 13–36% <1–10% rate % a 26% 9 % 25% 40% 53–60% • Lung cancer : 1st cause of cancer death (> 1,7 mil/ y) 3 • 13-18% total survival at 5 yrs 2 • NSCLC: 84% of all lung cancer 4 SURVIVAL 0 1 2 3 4 5 0% 20% 40% 60% 80% 100% Year
Table 1.Definitions of T, N, M (continued) N Regional Lymph Nodes NX Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis N1 Metastasis in ipsilateral peribronchial and/or ipsilateral N2 Hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension N3 Metastasis in ipsilateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicualar lymph node(s) M Distant Metastasis M0 No distant metastasis M1 Distant metastasis M1a Separate tumor nodule(s) in a contralateral lobe: tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion M1b Single extrathoracic metastasis in a single organ (including involvement of a single nonregional node) M1c Multiple extrathoracic metastasis in a single organ or in multiple organs Table 2. AJCC Prognostic Groups T N M T N M Occult TX N0 M0 Stage IIIB T1a N3 M0 Carcinoma T1b N3 M0 Stage 0 Tis N0 M0 T1c N3 M0 Stage IA1 T1mi N0 M0 T2a N3 M0 T1a N0 M1 T2b N3 M1 Stage IA2 T1b N0 M2 T3 N2 M2 Stage IA3 T1c N0 M3 T3 N2 M3 Stage IB T2a N0 M4 Stage IIIC T3 N3 M4 Stage IIA T2b N0 M5 T4 N3 M5 Stage IIB T1a N1 M6 Stage IVA Any T Any N M1a T1b N1 M7 Any T Any N M1b T1c N1 M8 Stage IVB Any T Any N M1c T2a N1 M9 T2b N0 M10 Stage IIIA T1a N2 M11 T1b N2 M12 T1c N2 M13 T2a N2 M14 T2b N2 M15 T3 N1 M16 T4 N0 M17 T4 N1 M18 T ≤3 cm T 3-4 cm T 4-5 cm T : 5-7 cm T >7 cm or any size invading more