Title (PCHS) PHARCHEM 4 - PHYSICOCHEMICAL AND INSTRUMENTAL METHODS USED IN PHARMACEUTICAL ANALYSES - CHROMATOGRAPHY (WITH PERMISSION).pdf ✅

CHROMATOGRAPHY PHARMACEUTICAL ANALYSIS 2
CHROMATOGRAPHY.  A process in which a solution of a mixture containing inert materials, drug principles and impurities is separated into its components while moving through a bed of fixed porous solid having different and reversible affinities for the substances being separated.
CHROMATOGRAPHY.  The separation of substances comes about because each component of the mixture possesses a different mobility by reason of differences in adsorption, partition solubility, vapor pressure, molecular size or ionic charge.
CHROMATOGRAPHY.  It is particularly useful as a means of separating and purifying complex and closely related chemical substances which are difficult if not impossible to separate by chemical methods based on differences in solubility and volatility.